Welcome to ISBN
Indian Synthetic Biology Network
What is Synthetic biology?
Synthetic biology is a rational and ground-up construction of biomolecular components towards applications. The construction may be in the native or a non-native setting.
Native refers to the redesign of existing pathways. Non native refers to the transfer of pathways across organisms.
Though the term was proposed 1970s, it was formally reintroduced in June 2004, first conference of synthetic biology at MIT
What makes synthetic biology unique?
Several aspects of Synthetic Biology are novel
1. Rational design and construction in biology
2. Genome-wide data sheet of part, device and circuits
3. The rules of composing an organism are unknown.
4. IEEE equivalent standards in biology do not exist.
5. installable pathways as plug-in, plug out apps
6. non ATGC DNA
7. Long DNA synthesis technology
8. Genome editing tools
You may want to have a look at the FAQs here
Looking back, the term 'genetic engineering' seems to be a misnomer! Clearly, people practiced ‘probability’ in the name of 'engineering'...
With the emergence of Synthetic biology, engineering biological systems has begun!
Pawan K. Dhar
Professor, School of Biotechnology, Jawaharlal Nehru University,
New Delhi 110067